USPSTF 2022: statin use for primary prevention of CVD in adults

The 2022 recommendation statement issued by the US Preventive Services Task Force on taking a statin to prevent cardiovascular disease in adults who do not already have it. The Task Force grades its advice by age, by risk factors and by the estimated chance of a cardiovascular event over the next ten years. This statement updates its 2016 recommendation.

Also called Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: US Preventive Services Task Force Recommendation Statement

  • Guideline
  • In this atlas

Overview

Technical summary

JAMA 2022;328(8):746-753, doi 10.1001/jama.2022.13044, PMID 35997723. The USPSTF page dates the final statement August 23, 2022. Only the PubMed abstract and that date line were read; the full statement was not. Grades as the abstract labels them: B for ages 40 to 75 with one or more risk factors (abnormal blood fats, diabetes, hypertension, smoking) and a 10-year risk, as estimated, of at least 10%; C for the same group at 7.5% to under 10%; and an I statement from age 76. The USPSTF permits reuse of its work only under its copyright notice, so this atlas states the recommendations in its own words, with a citation and a link.

About this guideline

Edition
2022 recommendation statement
Published
2022-08-23
Status
Not checked for a newer edition
Scope
Primary prevention of cardiovascular disease with statins in adults aged 40 or older without known cardiovascular disease.

Source

Document
Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: US Preventive Services Task Force Recommendation Statement
Publisher
JAMA
Edition note
Recommendation statement published in JAMA 2022;328(8):746-753. PubMed abstract and bibliographic data, plus the date line of the USPSTF recommendation page (both fetched 2026-10-15). The full statement, the evidence review and the Task Force grade definitions were not read. PubMed lists no correction to the statement.

Recommendations

  • Evidence is insufficient to recommend for or against: Statins effective 2022-08-23
  • Recommended: Statins effective 2022-08-23

Record details

Record id
cardio:guideline-uspstf-2022-statin
Content hash
2db1592a0a6ec3327f26ecf4d7d11b2316204b7158be686694a2de3912b60cd4