ISCHEMIA main results, NEJM 2020

The main results report of the ISCHEMIA trial, published in the New England Journal of Medicine in April 2020. It reports that an initial invasive strategy did not reduce ischemic cardiovascular events or death compared with an initial conservative strategy in people with stable coronary disease and moderate or severe ischemia.

Also called Initial Invasive or Conservative Strategy for Stable Coronary Disease

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Overview

Technical summary

N Engl J Med, 9 April 2020 (PubMed). DOI 10.1056/NEJMoa1915922; PMID 32227755. PubMed lists a PMC copy (PMC7263833) that is not in the PMC Open Access subset, so only the abstract was read. The author list includes the study chair named on the registry, Judith S Hochman.

In plain language

The abstract says the authors found no evidence that starting with an invasive strategy reduced the risk of ischemic cardiovascular events or death from any cause over a median of 3.2 years, and that the findings depended on how myocardial infarction was defined.

Bibliographic identity

Type
Article
Source
Initial Invasive or Conservative Strategy for Stable Coronary Disease
Edition
PubMed record (abstract and bibliographic data) from NCBI E-utilities. PMC lists a copy (PMC7263833) that is not in the PMC Open Access subset, so the full text was not fetched. The version of record was not fetched.
Publisher
The New England journal of medicine
Published
2020-04-09

Record details

Record id
cardio:pub-ischemia-nejm-2020
Content hash
16bec40d2847f7e97940092edafd555353da21a1b073147e7eff40d4b46df369