Cardiovascular Atlas
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Cardiovascular-kidney-metabolic (CKM) health

Cardiovascular-kidney-metabolic health is the way the American Heart Association's 2023 presidential advisory describes how metabolic risk factors, chronic kidney disease and the heart and blood vessels affect one another. The advisory says poor health in this area leads to many cardiovascular events and deaths, and that a growing number of treatments help metabolic risk factors, the kidneys or both while also protecting the heart. It calls for a clearer definition, a staging approach that supports prevention, prediction tools and care that joins up across specialties.

Also called Cardiovascular-kidney-metabolic syndrome

  • Care topic
  • In this atlas

Overview

Technical summary

Scope page for the advisory in Circulation 2023;148(20):1606-1635, doi 10.1161/CIR.0000000000001184, PMID 37807924. Only the abstract was read, so the stages, the definitions and the prediction tools in the advisory body are not recorded. PubMed lists one correction (2024-03-26), whose text was not read. The advisory is guidance from the AHA, not a trial result. The plan asked for the staging framework; the abstract only says that a staging approach is needed.

Scope

The combined effect of metabolic risk factors, chronic kidney disease and cardiovascular disease, as the AHA 2023 presidential advisory defines the field. The abstract speaks of the population in general and of staging across the life course.

Life stages

None stated

Care setting
Not reported

Claims and evidence

Context People with or at risk of cardiovascular-kidney-metabolic syndrome (AHA 2023 presidential advisory)

Recipient
Recipient not specified
Population
People with, or at risk of, cardiovascular-kidney-metabolic syndrome. The abstract speaks of the population in general, of poor health being most common where social determinants of health are adverse, and of staging that supports prevention across the life course. It gives no age limits.
Care setting
Not stated in the abstract. The abstract calls for care models that join up several specialties.
Geography
Not stated in the abstract (American Heart Association advisory; jurisdiction not verified)
Life stage
Across the life course, as the abstract words the aim of staging
Gestational age
Not reported
Postnatal age
Not reported
Follow-up
Not applicable (guideline context)
Eligibility: 1 inclusion criterion; exclusion criteria not stated
Included
  • People with, or at risk of, cardiovascular-kidney-metabolic syndrome
Excluded
None stated

  • Description Guidance Certainty not assessed

    The abstract of the American Heart Association 2023 presidential advisory describes cardiovascular-kidney-metabolic health as the way metabolic risk factors, chronic kidney disease and the heart and vessels act on one another. It says poor health in this area has multisystem consequences, the most significant being a high rate of cardiovascular events and cardiovascular death, and that more treatment options now help metabolic risk factors, kidney function or both while also protecting the heart. It calls for a clearer definition of the syndrome, a staging approach that supports prevention across the life course, prediction algorithms and harmonized prevention and management strategies.

    Source problem. A cited source is corrected. Check the sources before relying on this claim.

    Applies to Recipient not specified
    • People with, or at risk of, cardiovascular-kidney-metabolic syndrome. The abstract speaks of the population in general, of poor health being most common where social determinants of health are adverse, and of staging that supports prevention across the life course. It gives no age limits.
    • Not stated in the abstract. The abstract calls for care models that join up several specialties.
    • Not stated in the abstract (American Heart Association advisory; jurisdiction not verified)
    • Across the life course, as the abstract words the aim of staging
    • Gestational age Not reported
    • Postnatal age Not reported
    Follow-up Not applicable (guideline context)
    Certainty method
    Not assessed
    Limitations
    Only the abstract and the bibliographic record were read. The stages, the definitions and the prediction tools in the advisory body are not recorded. An advisory is guidance from the AHA, not a trial result. PubMed lists one correction (2024-03-26); its text was not read, so it is not known whether it changes anything stated here.
    Last checked
    2026-10-15
    Next evidence check due
    Not scheduled
    Sources and citations (5)

    1. Supports Cardiovascular-Kidney-Metabolic Health: A Presidential Advisory From the American Heart Association

      Publication · Circulation · Edition Published in Circulation 148(20):1606-1635 (issue date 2023-11-14; electronic publication 2023-10-09). PubMed abstract and bibliographic data only. PubMed lists no PMC copy. The advisory text was not read. PubMed lists 1 correction to the advisory; their text was not read. The publisher field is the journal title as PubMed gives it. · Published 2023-11-14 · DOI: 10.1161/CIR.0000000000001184 · PMID: 37807924

      Locator
      Abstract, sentences 1 and 2
      How it applies
      The definition and the consequences.
      Retrieved
      Source effective date
      Not reported
      Source state
      Corrected
      Snapshot hash
      66acc9065fe752997fbf67c9f761343e5bc91d2c47d45117347f56d8ef46fb39
      Reuse basis
      PubMed record fetched through NCBI E-utilities on 2026-10-15. Only the hash of the bytes is kept; nothing is committed. Bibliographic metadata and short quotations from the PubMed abstract, under 25 words each. The full text was not redistributed and the societies' reuse terms were not reviewed. Public text is quote under the PubMed abstract rule: only short quotations from the PubMed abstract, with attribution.

    2. Supports Cardiovascular-Kidney-Metabolic Health: A Presidential Advisory From the American Heart Association

      Publication · Circulation · Edition Published in Circulation 148(20):1606-1635 (issue date 2023-11-14; electronic publication 2023-10-09). PubMed abstract and bibliographic data only. PubMed lists no PMC copy. The advisory text was not read. PubMed lists 1 correction to the advisory; their text was not read. The publisher field is the journal title as PubMed gives it. · Published 2023-11-14 · DOI: 10.1161/CIR.0000000000001184 · PMID: 37807924

      Locator
      Abstract, sentence 4
      How it applies
      More treatment options help risk factors, kidney function or both, with cardioprotective effects.
      Retrieved
      Source effective date
      Not reported
      Source state
      Corrected
      Snapshot hash
      66acc9065fe752997fbf67c9f761343e5bc91d2c47d45117347f56d8ef46fb39
      Reuse basis
      PubMed record fetched through NCBI E-utilities on 2026-10-15. Only the hash of the bytes is kept; nothing is committed. Bibliographic metadata and short quotations from the PubMed abstract, under 25 words each. The full text was not redistributed and the societies' reuse terms were not reviewed. Public text is quote under the PubMed abstract rule: only short quotations from the PubMed abstract, with attribution.

    3. Supports Cardiovascular-Kidney-Metabolic Health: A Presidential Advisory From the American Heart Association

      Publication · Circulation · Edition Published in Circulation 148(20):1606-1635 (issue date 2023-11-14; electronic publication 2023-10-09). PubMed abstract and bibliographic data only. PubMed lists no PMC copy. The advisory text was not read. PubMed lists 1 correction to the advisory; their text was not read. The publisher field is the journal title as PubMed gives it. · Published 2023-11-14 · DOI: 10.1161/CIR.0000000000001184 · PMID: 37807924

      Locator
      Abstract, sentence 5
      How it applies
      The four needs the advisory names.
      Retrieved
      Source effective date
      Not reported
      Source state
      Corrected
      Snapshot hash
      66acc9065fe752997fbf67c9f761343e5bc91d2c47d45117347f56d8ef46fb39
      Reuse basis
      PubMed record fetched through NCBI E-utilities on 2026-10-15. Only the hash of the bytes is kept; nothing is committed. Bibliographic metadata and short quotations from the PubMed abstract, under 25 words each. The full text was not redistributed and the societies' reuse terms were not reviewed. Public text is quote under the PubMed abstract rule: only short quotations from the PubMed abstract, with attribution.

    4. Supports Cardiovascular-Kidney-Metabolic Health: A Presidential Advisory From the American Heart Association

      Publication · Circulation · Edition Published in Circulation 148(20):1606-1635 (issue date 2023-11-14; electronic publication 2023-10-09). PubMed abstract and bibliographic data only. PubMed lists no PMC copy. The advisory text was not read. PubMed lists 1 correction to the advisory; their text was not read. The publisher field is the journal title as PubMed gives it. · Published 2023-11-14 · DOI: 10.1161/CIR.0000000000001184 · PMID: 37807924

      Locator
      Abstract, sentence 7
      How it applies
      What the advisory provides guidance on.
      Retrieved
      Source effective date
      Not reported
      Source state
      Corrected
      Snapshot hash
      66acc9065fe752997fbf67c9f761343e5bc91d2c47d45117347f56d8ef46fb39
      Reuse basis
      PubMed record fetched through NCBI E-utilities on 2026-10-15. Only the hash of the bytes is kept; nothing is committed. Bibliographic metadata and short quotations from the PubMed abstract, under 25 words each. The full text was not redistributed and the societies' reuse terms were not reviewed. Public text is quote under the PubMed abstract rule: only short quotations from the PubMed abstract, with attribution.

    5. Background Cardiovascular-Kidney-Metabolic Health: A Presidential Advisory From the American Heart Association

      Publication · Circulation · Edition Published in Circulation 148(20):1606-1635 (issue date 2023-11-14; electronic publication 2023-10-09). PubMed abstract and bibliographic data only. PubMed lists no PMC copy. The advisory text was not read. PubMed lists 1 correction to the advisory; their text was not read. The publisher field is the journal title as PubMed gives it. · Published 2023-11-14 · DOI: 10.1161/CIR.0000000000001184 · PMID: 37807924

      Locator
      CommentsCorrectionsList, ErratumIn entry
      How it applies
      Shows that a correction exists. What it changes is unknown.
      Retrieved
      Source effective date
      Not reported
      Source state
      Corrected
      Snapshot hash
      66acc9065fe752997fbf67c9f761343e5bc91d2c47d45117347f56d8ef46fb39
      Reuse basis
      PubMed record fetched through NCBI E-utilities on 2026-10-15. Only the hash of the bytes is kept; nothing is committed. Bibliographic metadata and short quotations from the PubMed abstract, under 25 words each. The full text was not redistributed and the societies' reuse terms were not reviewed. Public text is quote under the PubMed abstract rule: only short quotations from the PubMed abstract, with attribution.

Record details

Record id
cardio:cardiovascular-kidney-metabolic-health
Content hash
a08f5811e02051f1591c4a04954084d20f45667fce9c22c7e2fdfda2c418d34f