{
  "release_id": "2b2017b84496b985",
  "entries": [
    {
      "id": "cardio:pub-esc-2024-hypertension",
      "name": "2024 ESC guidelines on elevated blood pressure and hypertension",
      "aliases": [
        "2024 ESC Guidelines for the management of elevated blood pressure and hypertension"
      ],
      "kind": "publication",
      "kind_label": "Publication",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "The 2024 guideline from the European Society of Cardiology on elevated blood pressure and hypertension. It updates the society's 2018 guideline, which it...",
      "route": "publications/pub-esc-2024-hypertension/"
    },
    {
      "id": "cardio:pub-aha-acc-2025-hbp",
      "name": "2025 AHA/ACC high blood pressure guideline",
      "aliases": [
        "2025 AHA/ACC guideline for high blood pressure in adults"
      ],
      "kind": "publication",
      "kind_label": "Publication",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "The 2025 guideline from the American Heart Association and the American College of Cardiology, with other societies, on preventing, detecting, evaluating and...",
      "route": "publications/pub-aha-acc-2025-hbp/"
    },
    {
      "id": "cardio:outcome-sprint-acs-not-mi",
      "name": "Acute coronary syndrome not resulting in myocardial infarction (SPRINT component)",
      "aliases": [
        "Acute coronary syndrome"
      ],
      "kind": "outcome",
      "kind_label": "Outcome",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "A sudden heart-artery problem that did not lead to a heart attack. In SPRINT it is one of the five kinds of event that made up the primary combined outcome.",
      "route": "outcomes/outcome-sprint-acs-not-mi/"
    },
    {
      "id": "cardio:outcome-sprint-acute-decompensated-heart-failure",
      "name": "Acute decompensated heart failure (SPRINT component)",
      "aliases": [
        "Heart failure"
      ],
      "kind": "outcome",
      "kind_label": "Outcome",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "A sudden worsening of heart failure. In SPRINT it is one of the five kinds of event that made up the primary combined outcome.",
      "route": "outcomes/outcome-sprint-acute-decompensated-heart-failure/"
    },
    {
      "id": "cardio:ambulatory-bp-monitoring",
      "name": "Ambulatory blood pressure monitoring (ABPM)",
      "aliases": [
        "ABPM"
      ],
      "kind": "intervention",
      "kind_label": "Intervention",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "Taking repeated blood pressure readings while a person goes about a normal waking day, to check whether a high reading in the clinic is confirmed.",
      "route": "interventions/ambulatory-bp-monitoring/"
    },
    {
      "id": "core:acc",
      "name": "American College of Cardiology",
      "aliases": [
        "ACC"
      ],
      "kind": "organization",
      "kind_label": "Organization",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "A membership organization in the United States for the people who work in cardiovascular care and research.",
      "route": "organizations/acc/"
    },
    {
      "id": "core:aha",
      "name": "American Heart Association",
      "aliases": [
        "AHA"
      ],
      "kind": "organization",
      "kind_label": "Organization",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "A nonprofit organization in the United States that the Research Organization Registry also lists as a funder.",
      "route": "organizations/aha/"
    },
    {
      "id": "core:automated-upper-arm-cuff-device",
      "name": "Automated upper-arm cuff blood pressure device",
      "aliases": [],
      "kind": "technology",
      "kind_label": "Technology",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "A blood pressure device with a cuff for the upper arm that works out the reading itself from signals in the cuff.",
      "route": "technologies/automated-upper-arm-cuff-device/"
    },
    {
      "id": "core:blood-pressure",
      "name": "Blood pressure",
      "aliases": [
        "BP"
      ],
      "kind": "biomarker",
      "kind_label": "Biomarker",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "How hard the blood pushes on the arteries and other blood vessels. Oscillometric blood pressure devices estimate a systolic value and a diastolic value.",
      "route": "biomarkers/blood-pressure/"
    },
    {
      "id": "cardio:bp-lowering-medicine",
      "name": "Blood pressure lowering medicine",
      "aliases": [
        "Antihypertensive medicine",
        "Antihypertensive drug treatment"
      ],
      "kind": "intervention",
      "kind_label": "Intervention",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "Medicines that lower blood pressure, started and adjusted for adults whose high blood pressure is confirmed.",
      "route": "interventions/bp-lowering-medicine/"
    },
    {
      "id": "cardio:bp-lowering-to-target",
      "name": "Blood-pressure lowering to a target",
      "aliases": [],
      "kind": "intervention",
      "kind_label": "Intervention",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "Using medicines and lifestyle changes to bring blood pressure below a chosen number and keep it there.",
      "route": "interventions/bp-lowering-to-target/"
    },
    {
      "id": "cardio:pub-bplttc-lancet-2021",
      "name": "BPLTTC individual-participant meta-analysis, Lancet 2021",
      "aliases": [
        "Blood Pressure Lowering Treatment Trialists' Collaboration 2021"
      ],
      "kind": "publication",
      "kind_label": "Publication",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "A large analysis that pooled the original patient-level data from 48 randomised trials of blood-pressure-lowering medicines, 344,716 people in all. It asked...",
      "route": "publications/pub-bplttc-lancet-2021/"
    },
    {
      "id": "cardio:bruce-neal",
      "name": "Bruce Neal",
      "aliases": [],
      "kind": "person",
      "kind_label": "Person",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "Bruce Neal is a medical researcher whose public ORCID record lists a post, with no end date, at The George Institute for Global Health in Sydney (the record's...",
      "route": "people/bruce-neal/"
    },
    {
      "id": "cardio:ssass",
      "name": "China Salt Substitute and Stroke Study (SSaSS)",
      "aliases": [
        "SSaSS",
        "Salt Substitute and Stroke Study"
      ],
      "kind": "study",
      "kind_label": "Study",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "A large trial in rural China that tested whether replacing ordinary salt with a lower-sodium, potassium-enriched salt reduces strokes. It enrolled people who...",
      "route": "studies/ssass/"
    },
    {
      "id": "cardio:idea-cuffless-bp-monitoring",
      "name": "Cuffless blood pressure monitoring",
      "aliases": [
        "Cuffless wearable blood pressure devices"
      ],
      "kind": "idea",
      "kind_label": "Idea",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "Many devices that measure blood pressure without an inflating cuff are on sale, and they claim to be accurate. A European hypertension expert group says they...",
      "route": "ideas/idea-cuffless-bp-monitoring/"
    },
    {
      "id": "core:outcome-death-any-cause",
      "name": "Death from any cause",
      "aliases": [
        "All-cause mortality"
      ],
      "kind": "outcome",
      "kind_label": "Outcome",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "Dying for any reason during a study's follow-up.",
      "route": "outcomes/outcome-death-any-cause/"
    },
    {
      "id": "cardio:outcome-sprint-cv-death",
      "name": "Death from cardiovascular causes (SPRINT component)",
      "aliases": [
        "CVD death"
      ],
      "kind": "outcome",
      "kind_label": "Outcome",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "Death from heart or blood-vessel causes. In SPRINT it is one of the five kinds of event that made up the primary combined outcome.",
      "route": "outcomes/outcome-sprint-cv-death/"
    },
    {
      "id": "cardio:reading-path-high-bp",
      "name": "From a high blood pressure reading to stroke prevention",
      "aliases": [
        "Reading path: high blood pressure"
      ],
      "kind": "reading_path",
      "kind_label": "Reading path",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "A suggested order for reading this atlas, for an adult who has been told they have a high blood pressure reading, and for their family. It starts with what a...",
      "route": "reading-paths/reading-path-high-bp/"
    },
    {
      "id": "cardio:high-sodium-intake",
      "name": "High sodium intake",
      "aliases": [
        "High salt intake"
      ],
      "kind": "risk_factor",
      "kind_label": "Risk factor",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "Sodium is the part of table salt linked with higher blood pressure when people eat a lot of it. The World Health Organization advises adults to keep sodium...",
      "route": "risk-factors/high-sodium-intake/"
    },
    {
      "id": "core:home-bp-monitoring",
      "name": "Home blood pressure monitoring",
      "aliases": [
        "Self-measured blood pressure monitoring",
        "SMBP",
        "HBPM"
      ],
      "kind": "intervention",
      "kind_label": "Intervention",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "Measuring your own blood pressure with a device, at home or somewhere else outside the clinic.",
      "route": "interventions/home-bp-monitoring/"
    },
    {
      "id": "core:hypertension",
      "name": "Hypertension (high blood pressure)",
      "aliases": [
        "High blood pressure"
      ],
      "kind": "condition",
      "kind_label": "Condition",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "Blood pressure that stays higher than it should over time.",
      "route": "conditions/hypertension/"
    },
    {
      "id": "cardio:nonphysician-hypertension-treatment",
      "name": "Hypertension treatment by nonphysician professionals, such as pharmacists and nurses",
      "aliases": [
        "Nonphysician hypertension treatment"
      ],
      "kind": "intervention",
      "kind_label": "Intervention",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "Health professionals who are not doctors, such as pharmacists and nurses, providing blood pressure medicine, as long as they have proper training and...",
      "route": "interventions/nonphysician-hypertension-treatment/"
    },
    {
      "id": "cardio:intensive-sbp-lowering",
      "name": "Intensive systolic blood-pressure lowering (target below 120 mm Hg)",
      "aliases": [],
      "kind": "intervention",
      "kind_label": "Intervention",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "A treatment plan that adjusts blood-pressure medicines until the top number is under 120, rather than the more usual under 140.",
      "route": "interventions/intensive-sbp-lowering/"
    },
    {
      "id": "cardio:mrc",
      "name": "Medical Research Council (United Kingdom)",
      "aliases": [
        "MRC"
      ],
      "kind": "organization",
      "kind_label": "Organization",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "A UK research funder that PubMed lists for the SSaSS paper.",
      "route": "organizations/mrc/"
    },
    {
      "id": "cardio:outcome-sprint-myocardial-infarction",
      "name": "Myocardial infarction (SPRINT component)",
      "aliases": [],
      "kind": "outcome",
      "kind_label": "Outcome",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "A heart attack. In SPRINT it is one of the five kinds of event that made up the primary combined outcome.",
      "route": "outcomes/outcome-sprint-myocardial-infarction/"
    },
    {
      "id": "cardio:nhmrc",
      "name": "National Health and Medical Research Council of Australia",
      "aliases": [
        "NHMRC"
      ],
      "kind": "organization",
      "kind_label": "Organization",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "An Australian research funder named by the SSaSS paper as its funder.",
      "route": "organizations/nhmrc/"
    },
    {
      "id": "cardio:nhlbi",
      "name": "National Heart, Lung, and Blood Institute",
      "aliases": [
        "NHLBI"
      ],
      "kind": "organization",
      "kind_label": "Organization",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "The US government institute that funds heart, lung and blood research.",
      "route": "organizations/nhlbi/"
    },
    {
      "id": "cardio:nice",
      "name": "National Institute for Health and Care Excellence",
      "aliases": [
        "NICE"
      ],
      "kind": "organization",
      "kind_label": "Organization",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "The organization that publishes the NICE guidelines, including the guideline on high blood pressure in adults.",
      "route": "organizations/nice/"
    },
    {
      "id": "cardio:niddk",
      "name": "National Institute of Diabetes and Digestive and Kidney Diseases",
      "aliases": [
        "NIDDK"
      ],
      "kind": "organization",
      "kind_label": "Organization",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "A US government institute that funds research on diabetes, digestion and kidney disease.",
      "route": "organizations/niddk/"
    },
    {
      "id": "cardio:ninds",
      "name": "National Institute of Neurological Disorders and Stroke",
      "aliases": [
        "NINDS"
      ],
      "kind": "organization",
      "kind_label": "Organization",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "A US government institute that funds brain and nervous-system research.",
      "route": "organizations/ninds/"
    },
    {
      "id": "cardio:nia",
      "name": "National Institute on Aging",
      "aliases": [
        "NIA"
      ],
      "kind": "organization",
      "kind_label": "Organization",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "A US government institute that funds research on aging.",
      "route": "organizations/nia/"
    },
    {
      "id": "cardio:nih",
      "name": "National Institutes of Health",
      "aliases": [
        "NIH"
      ],
      "kind": "organization",
      "kind_label": "Organization",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "The National Institutes of Health, named as the funder of the SPRINT trial. The NHLBI, NIDDK, NINDS and NIA are among its institutes.",
      "route": "organizations/nih/"
    },
    {
      "id": "cardio:pub-nice-ng136",
      "name": "NICE guideline NG136: Hypertension in adults, diagnosis and management",
      "aliases": [],
      "kind": "publication",
      "kind_label": "Publication",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "The NICE guideline on diagnosing and treating high blood pressure in adults, with the dates of its changes.",
      "route": "publications/pub-nice-ng136/"
    },
    {
      "id": "cardio:omron-healthcare",
      "name": "Omron Healthcare, Inc.",
      "aliases": [
        "Omron Healthcare"
      ],
      "kind": "organization",
      "kind_label": "Organization",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "The company named as the applicant on the 2000 US FDA clearance of the Omron HEM-907 blood pressure monitor. This page records the name as the FDA gives it. It...",
      "route": "organizations/omron-healthcare/"
    },
    {
      "id": "cardio:omron-hem-907",
      "name": "Omron HEM-907 blood pressure monitor",
      "aliases": [
        "HEM-907",
        "Omron IntelliSense blood pressure monitor, model HEM-907"
      ],
      "kind": "product",
      "kind_label": "Product",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "An electronic blood pressure monitor, the Omron HEM-907. The US Food and Drug Administration cleared it in 2000. The FDA record names Omron Healthcare, Inc...",
      "route": "products/omron-hem-907/"
    },
    {
      "id": "cardio:cardiovascular-prevention",
      "name": "Preventing heart attack, stroke and heart failure",
      "aliases": [
        "Cardiovascular prevention"
      ],
      "kind": "care_topic",
      "kind_label": "Care topic",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "This page is the starting point for the atlas's prevention material. For now it is built around blood pressure, because the first evidence recorded here is...",
      "route": "care-topics/cardiovascular-prevention/"
    },
    {
      "id": "cardio:salt-substitution",
      "name": "Salt substitution (lower-sodium, potassium-containing salt)",
      "aliases": [
        "Lower-sodium salt substitutes",
        "LSSS"
      ],
      "kind": "intervention",
      "kind_label": "Intervention",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "Swapping ordinary table salt for a salt that has part of its sodium replaced with potassium. The aim is lower blood pressure and, over years, fewer strokes. In...",
      "route": "interventions/salt-substitution/"
    },
    {
      "id": "cardio:outcome-sprint-primary-composite",
      "name": "SPRINT primary composite cardiovascular outcome",
      "aliases": [],
      "kind": "outcome",
      "kind_label": "Outcome",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "A combined count of heart attacks, other sudden heart-artery problems, strokes, heart failure and deaths from heart or blood-vessel causes.",
      "route": "outcomes/outcome-sprint-primary-composite/"
    },
    {
      "id": "cardio:pub-sprint-nejm-2015",
      "name": "SPRINT primary results, NEJM 2015",
      "aliases": [],
      "kind": "publication",
      "kind_label": "Publication",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "The main report of the SPRINT trial results, published in November 2015.",
      "route": "publications/pub-sprint-nejm-2015/"
    },
    {
      "id": "cardio:pub-ssass-nejm-2021",
      "name": "SSaSS main results, NEJM 2021",
      "aliases": [],
      "kind": "publication",
      "kind_label": "Publication",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "The main report of the SSaSS salt-substitute trial, published online on 29 August 2021 and in the print issue of 16 September 2021.",
      "route": "publications/pub-ssass-nejm-2021/"
    },
    {
      "id": "cardio:stride-bp-validated-device-lists",
      "name": "STRIDE BP validated device lists",
      "aliases": [
        "STRIDE BP validated devices lists"
      ],
      "kind": "resource",
      "kind_label": "Resource",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "STRIDE BP is a group that keeps lists of validated blood pressure monitors on its website, https://www.stridebp.org/. Its terms do not allow its content to be...",
      "route": "resources/stride-bp-validated-device-lists/"
    },
    {
      "id": "core:stroke",
      "name": "Stroke",
      "aliases": [],
      "kind": "condition",
      "kind_label": "Condition",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "A sudden loss of brain function. It happens when part of the brain does not get enough blood or when there is bleeding inside the skull.",
      "route": "conditions/stroke/"
    },
    {
      "id": "core:outcome-stroke",
      "name": "Stroke as an outcome",
      "aliases": [],
      "kind": "outcome",
      "kind_label": "Outcome",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "Having a stroke during a study's follow-up. Each study decides what counts as a stroke.",
      "route": "outcomes/outcome-stroke/"
    },
    {
      "id": "cardio:sprint",
      "name": "Systolic Blood Pressure Intervention Trial (SPRINT)",
      "aliases": [
        "SPRINT"
      ],
      "kind": "study",
      "kind_label": "Study",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "A large US trial that compared aiming for a top blood-pressure number below 120 with aiming below 140 in adults aged 50 and over at higher heart risk who did...",
      "route": "studies/sprint/"
    },
    {
      "id": "core:george-institute",
      "name": "The George Institute for Global Health",
      "aliases": [
        "The George Institute"
      ],
      "kind": "organization",
      "kind_label": "Organization",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "A global health research organisation and registered charity. It says it has major centres in Australia, the UK, China and India.",
      "route": "organizations/george-institute/"
    },
    {
      "id": "core:lancet",
      "name": "The Lancet",
      "aliases": [
        "Lancet"
      ],
      "kind": "journal",
      "kind_label": "Journal",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "A medical journal published by Elsevier.",
      "route": "journals/lancet/"
    },
    {
      "id": "core:nejm",
      "name": "The New England Journal of Medicine",
      "aliases": [
        "N Engl J Med",
        "NEJM"
      ],
      "kind": "journal",
      "kind_label": "Journal",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "A general medical journal that published the main reports of the SPRINT and iKMC trials.",
      "route": "journals/nejm/"
    },
    {
      "id": "core:fda",
      "name": "U.S. Food and Drug Administration",
      "aliases": [
        "FDA",
        "United States Food and Drug Administration"
      ],
      "kind": "organization",
      "kind_label": "Organization",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "The US federal agency that regulates drugs, biological products and medical devices, and that is also responsible for the safety of food and cosmetics.",
      "route": "organizations/fda/"
    },
    {
      "id": "cardio:wake-forest-health-sciences",
      "name": "Wake Forest University Health Sciences",
      "aliases": [],
      "kind": "organization",
      "kind_label": "Organization",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "A US academic health center listed as a SPRINT collaborator.",
      "route": "organizations/wake-forest-health-sciences/"
    },
    {
      "id": "cardio:pub-who-2021-hypertension-pharmacological",
      "name": "WHO guideline for the pharmacological treatment of hypertension in adults (2021)",
      "aliases": [],
      "kind": "publication",
      "kind_label": "Publication",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "The 2021 World Health Organization guideline on when to start blood pressure medicine in adults, which medicines to start with, which targets to aim for and...",
      "route": "publications/pub-who-2021-hypertension-pharmacological/"
    },
    {
      "id": "cardio:who",
      "name": "World Health Organization",
      "aliases": [
        "WHO"
      ],
      "kind": "organization",
      "kind_label": "Organization",
      "editorial_state": "draft",
      "state_pill": null,
      "snippet": "The World Health Organization, which publishes the three guidelines this atlas records: on medicines for high blood pressure in adults (2021), on lower-sodium...",
      "route": "organizations/who/"
    }
  ]
}