{
  "release_id": "73130c34862e2d06",
  "id": "cardio:novartis",
  "owner": "cardio",
  "kind": "organization",
  "slug": "novartis",
  "name": "Novartis",
  "aliases": [
    "Novartis AG",
    "Novartis Pharmaceuticals"
  ],
  "atlases": [
    "cardio"
  ],
  "summary_plain": "Novartis is a Swiss drug company. It makes Leqvio (inclisiran), is a collaborator on the ORION-4 inclisiran outcome trial, and sponsored the Lp(a)HORIZON trial of pelacarsen, which it reported in September 2026 had missed its main goal.",
  "summary_technical": "ROR record 02f9zrr09, Switzerland, listed with the types company and funder. The Leqvio label record gives Novartis Pharmaceuticals Corporation as manufacturer and the US drug-approvals database gives NOVARTIS as applicant on NDA214012. ClinicalTrials.gov lists Novartis Pharmaceuticals as lead sponsor of Lp(a)HORIZON (NCT04023552) and as a collaborator on ORION-4 (NCT03705234). The registry names the entity Novartis Pharmaceuticals and the ROR record names the parent company; this page treats them as one organization for navigation.",
  "editorial_state": "draft",
  "last_substantive_edit": "2026-10-15",
  "last_evidence_check": "2026-10-14",
  "next_review_due": null,
  "identifiers": [
    {
      "scheme": "ror",
      "value": "02f9zrr09",
      "normalized_value": "02f9zrr09",
      "match": "exact",
      "version": null,
      "label": null,
      "from_source": false
    }
  ],
  "navigation": null,
  "payload": {
    "roles": [
      "company"
    ],
    "sector": "industry"
  },
  "content_digest": "5fb1984c457a00e924ddc97de0b108647524d5f11f3e068e03b8ac054385a21c",
  "review": {
    "content_digest": "5fb1984c457a00e924ddc97de0b108647524d5f11f3e068e03b8ac054385a21c",
    "current": [],
    "conflicting": [],
    "stale": [],
    "inactive": []
  },
  "claims": [],
  "decisions": [],
  "milestones": [],
  "relationships": {
    "outgoing": [],
    "incoming": [
      {
        "predicate": "manufactured_by",
        "label": "Manufactures",
        "clinical_claim_not_fact": false,
        "family": "sourced",
        "other_entity_id": "cardio:entresto",
        "other_entity_in_atlas": true,
        "claim_id": null,
        "evidence": {
          "snapshot_id": "cardio:openfda-nda207620-2026-10-14",
          "locator": "results[0].openfda.manufacturer_name[0]"
        },
        "primary": false,
        "role": null,
        "valid_from": null,
        "valid_to": null
      },
      {
        "predicate": "manufactured_by",
        "label": "Manufactures",
        "clinical_claim_not_fact": false,
        "family": "sourced",
        "other_entity_id": "cardio:leqvio",
        "other_entity_in_atlas": true,
        "claim_id": null,
        "evidence": {
          "snapshot_id": "cardio:openfda-label-6fc0afca-4513-4c35-b594-6544aee29a44-2026-10-14",
          "locator": "results[0].openfda.manufacturer_name[0]"
        },
        "primary": false,
        "role": null,
        "valid_from": null,
        "valid_to": null
      },
      {
        "predicate": "sponsored_by",
        "label": "Sponsors",
        "clinical_claim_not_fact": false,
        "family": "sourced",
        "other_entity_id": "cardio:orion-4",
        "other_entity_in_atlas": true,
        "claim_id": null,
        "evidence": {
          "snapshot_id": "cardio:ctgov-nct03705234-2026-10-14",
          "locator": "protocolSection.sponsorCollaboratorsModule.collaborators[1].name"
        },
        "primary": false,
        "role": "collaborator",
        "valid_from": null,
        "valid_to": null
      },
      {
        "predicate": "sponsored_by",
        "label": "Sponsors",
        "clinical_claim_not_fact": false,
        "family": "sourced",
        "other_entity_id": "cardio:paradigm-hf",
        "other_entity_in_atlas": true,
        "claim_id": null,
        "evidence": {
          "snapshot_id": "cardio:ctgov-nct01035255-2026-10-14",
          "locator": "protocolSection.sponsorCollaboratorsModule.leadSponsor.name"
        },
        "primary": false,
        "role": "lead",
        "valid_from": null,
        "valid_to": null
      }
    ]
  },
  "page_path": "organizations/novartis/",
  "context_path": "api/v1/context/cardio--novartis.md"
}