{
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  "id": "cardio:intensive-sbp-lowering",
  "owner": "cardio",
  "kind": "intervention",
  "slug": "intensive-sbp-lowering",
  "name": "Intensive systolic blood-pressure lowering (target below 120 mm Hg)",
  "aliases": [],
  "atlases": [
    "cardio"
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  "summary_plain": "A treatment plan that adjusts blood-pressure medicines until the top number is under 120, rather than the more usual under 140.",
  "summary_technical": "Treat-to-target antihypertensive strategy with a systolic goal below 120 mm Hg, as tested in SPRINT. It is a strategy, not a specific drug.",
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  "navigation": {
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      "system": [
        "blood-vessels"
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      "condition-area": [
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      "context": {
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        "recipient": "adult",
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      "statement": "In SPRINT, adults aged 50 and over at raised heart risk, without diabetes or a past stroke, whose treatment aimed for a top (systolic) blood pressure below 120 mm Hg had fewer major heart and blood-vessel events than those aiming for below 140. Over a median of 3.26 years, 243 of 4678 people in the lower-target group and 319 of 4683 in the standard group had a first primary-outcome event (hazard ratio 0.75, 95% CI 0.64 to 0.89).",
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