{
  "release_id": "5dcd9b263fe17744",
  "id": "cardio:hearts-bangladesh",
  "owner": "cardio",
  "kind": "study",
  "slug": "hearts-bangladesh",
  "name": "WHO HEARTS evaluation in Bangladesh",
  "aliases": [
    "HEARTS Package Evaluation Trial in Bangladesh"
  ],
  "atlases": [
    "cardio"
  ],
  "summary_plain": "A study in rural Bangladesh that compared 7 primary healthcare clinics using the HEARTS hypertension control package with 7 matched clinics giving usual hypertension care. Clinics were matched and not randomly assigned. 3935 adults with uncontrolled hypertension took part. At 6 months, blood pressure had fallen further and more people had their blood pressure under control in the HEARTS clinics, and fewer clinic visits were missed.",
  "summary_technical": "Matched-pair cluster quasi-experimental trial (NCT04992039), registry allocation non-randomized, masking single, primary purpose health services research, phase not applicable. Lead sponsor National Heart Foundation of Bangladesh on the registry record. Registry dates: start 2021-10-09, primary completion 2021-12-31, completion 2022-08-12; the primary completion date is earlier than the 6-month follow-up the paper describes, and the two are not reconciled here. The paper (Heart, 2024) is open access under CC BY 4.0. Numbers are on the claim.",
  "editorial_state": "draft",
  "last_substantive_edit": "2026-10-15",
  "last_evidence_check": "2026-10-15",
  "next_review_due": null,
  "identifiers": [
    {
      "scheme": "nct",
      "value": "NCT04992039",
      "normalized_value": "NCT04992039",
      "match": "exact",
      "version": null,
      "label": null,
      "from_source": false
    }
  ],
  "navigation": {
    "cardio": {
      "system": [
        "blood-vessels"
      ],
      "condition-area": [
        "hypertension"
      ]
    }
  },
  "payload": {
    "design": "Matched-pair cluster quasi-experimental trial: 7 clinics implementing the HEARTS package and 7 matched usual care clinics. The registry records allocation as non-randomized and masking as single.",
    "drug_phase": "not_applicable",
    "registry_statuses": [
      {
        "status": "COMPLETED",
        "snapshot": "cardio:ctgov-nct04992039-2026-10-15"
      }
    ],
    "start_date": {
      "date": "2021-10-09",
      "type": "actual",
      "snapshot": "cardio:ctgov-nct04992039-2026-10-15"
    },
    "primary_completion_date": {
      "date": "2021-12-31",
      "type": "actual",
      "snapshot": "cardio:ctgov-nct04992039-2026-10-15"
    },
    "completion_date": {
      "date": "2022-08-12",
      "type": "actual",
      "snapshot": "cardio:ctgov-nct04992039-2026-10-15"
    },
    "results_first_posted": null,
    "countries": [
      {
        "code": "BD",
        "snapshot": "cardio:ctgov-nct04992039-2026-10-15"
      }
    ],
    "care_setting": {
      "description": "Fourteen Upazila Health Complexes, which are primary healthcare facilities, in rural Bangladesh (paper).",
      "snapshot": "cardio:pmc-pmc11347191-2026-10-15"
    },
    "stopped_early": null,
    "enrollment": [
      {
        "count": 3935,
        "basis": "enrolled",
        "unit": "participants",
        "snapshot": "cardio:ctgov-nct04992039-2026-10-15"
      }
    ],
    "arms": [
      {
        "id": "cardio:hearts-bangladesh-arm-hearts",
        "label": "HEARTS clinics",
        "intervention": "cardio:who-hearts",
        "description": "Clinics implementing all components of the HEARTS technical package (registry)."
      },
      {
        "id": "cardio:hearts-bangladesh-arm-usual-care",
        "label": "Usual care clinics",
        "intervention": null,
        "description": "Matched clinics continuing usual hypertension care (abstract); the registry says these participants did not receive the total HEARTS package."
      }
    ],
    "findings": []
  },
  "content_digest": "769dbd75ca0ffba6e0c1e28c6afb48bfaa96d51da97e2cd22aa27831cc574930",
  "review": {
    "content_digest": "769dbd75ca0ffba6e0c1e28c6afb48bfaa96d51da97e2cd22aa27831cc574930",
    "current": [],
    "conflicting": [],
    "stale": [],
    "inactive": []
  },
  "claims": [],
  "decisions": [],
  "milestones": [],
  "relationships": {
    "outgoing": [
      {
        "predicate": "investigates",
        "label": "Tests this package",
        "clinical_claim_not_fact": false,
        "family": "sourced",
        "other_entity_id": "cardio:who-hearts",
        "other_entity_in_atlas": true,
        "claim_id": null,
        "evidence": {
          "snapshot_id": "cardio:ctgov-nct04992039-2026-10-15",
          "locator": "protocolSection.armsInterventionsModule.interventions[0].name"
        },
        "primary": false,
        "role": null,
        "valid_from": null,
        "valid_to": null
      },
      {
        "predicate": "investigates",
        "label": "Studies people with this condition",
        "clinical_claim_not_fact": false,
        "family": "sourced",
        "other_entity_id": "core:hypertension",
        "other_entity_in_atlas": true,
        "claim_id": null,
        "evidence": {
          "snapshot_id": "cardio:ctgov-nct04992039-2026-10-15",
          "locator": "protocolSection.conditionsModule.conditions[0]"
        },
        "primary": false,
        "role": null,
        "valid_from": null,
        "valid_to": null
      }
    ],
    "incoming": []
  },
  "page_path": "studies/hearts-bangladesh/",
  "context_path": "api/v1/context/cardio--hearts-bangladesh.md"
}