{
  "release_id": "f6f6f1b6f50379ed",
  "id": "cardio:heart-valve-disease",
  "owner": "cardio",
  "kind": "condition",
  "slug": "heart-valve-disease",
  "name": "Heart valve disease",
  "aliases": [
    "Heart valve diseases",
    "Valvular heart disease"
  ],
  "atlases": [
    "cardio"
  ],
  "summary_plain": "Heart valve disease means that at least one of the heart's four valves is not working properly. A valve can leak backward (regurgitation), can be too narrow (stenosis), or can lack an opening (atresia). Some people are born with a valve problem. In others it develops with age or after an infection. A US government patient page says most valve conditions are treatable, with medicine, a repair or a replacement.",
  "summary_technical": "Parent record for the valve conditions in this atlas: aortic stenosis, mitral regurgitation and rheumatic heart disease. A US government patient page names three types of heart valve disease (regurgitation, stenosis and atresia). MeSH D006349 (Heart Valve Diseases) is the matching heading. The atlas has no separate tricuspid regurgitation record, so the records of the tricuspid repair device and its pivotal trial file their link under this one. Replacement and repair covered here: transcatheter aortic valve replacement, surgical aortic valve replacement and transcatheter edge-to-edge repair.",
  "editorial_state": "draft",
  "last_substantive_edit": "2026-10-15",
  "last_evidence_check": "2026-10-14",
  "next_review_due": null,
  "identifiers": [
    {
      "scheme": "mesh",
      "value": "D006349",
      "normalized_value": "D006349",
      "match": "exact",
      "version": "linked-data record read 2026-10-14",
      "label": null,
      "from_source": false
    }
  ],
  "navigation": {
    "cardio": {
      "system": [
        "heart"
      ],
      "condition-area": [
        "valvular-and-congenital-disease"
      ]
    }
  },
  "payload": {
    "recognition": "A US government patient page says a doctor may ask about symptoms, listen to the heart or order imaging tests, and that a person can have a valve problem without symptoms.",
    "assessment": null,
    "burden_claims": []
  },
  "content_digest": "613717fbc3f26418894403b73f1953c497d0471e1ce6f17156616ec4fa8fed95",
  "review": {
    "content_digest": "613717fbc3f26418894403b73f1953c497d0471e1ce6f17156616ec4fa8fed95",
    "current": [],
    "conflicting": [],
    "stale": [],
    "inactive": []
  },
  "claims": [],
  "decisions": [],
  "milestones": [],
  "relationships": {
    "outgoing": [
      {
        "predicate": "related_to",
        "label": "Valve replacement through a catheter",
        "clinical_claim_not_fact": false,
        "family": "navigation",
        "other_entity_id": "cardio:tavr",
        "other_entity_in_atlas": true,
        "claim_id": null,
        "evidence": null,
        "primary": false,
        "role": null,
        "valid_from": null,
        "valid_to": null
      },
      {
        "predicate": "part_of",
        "label": "Filed under this front",
        "clinical_claim_not_fact": false,
        "family": "navigation",
        "other_entity_id": "cardio:front-procedures-and-surgery",
        "other_entity_in_atlas": true,
        "claim_id": null,
        "evidence": null,
        "primary": true,
        "role": null,
        "valid_from": null,
        "valid_to": null
      }
    ],
    "incoming": [
      {
        "predicate": "related_to",
        "label": "Related to",
        "clinical_claim_not_fact": false,
        "family": "navigation",
        "other_entity_id": "core:medlineplus",
        "other_entity_in_atlas": true,
        "claim_id": null,
        "evidence": null,
        "primary": false,
        "role": null,
        "valid_from": null,
        "valid_to": null
      },
      {
        "predicate": "related_to",
        "label": "Related to",
        "clinical_claim_not_fact": false,
        "family": "navigation",
        "other_entity_id": "core:echocardiography",
        "other_entity_in_atlas": true,
        "claim_id": null,
        "evidence": null,
        "primary": false,
        "role": null,
        "valid_from": null,
        "valid_to": null
      },
      {
        "predicate": "related_to",
        "label": "Related to",
        "clinical_claim_not_fact": false,
        "family": "navigation",
        "other_entity_id": "cardio:adult-congenital-heart-disease",
        "other_entity_in_atlas": true,
        "claim_id": null,
        "evidence": null,
        "primary": false,
        "role": null,
        "valid_from": null,
        "valid_to": null
      },
      {
        "predicate": "subtype_of",
        "label": "Has subtype",
        "clinical_claim_not_fact": false,
        "family": "navigation",
        "other_entity_id": "cardio:aortic-stenosis",
        "other_entity_in_atlas": true,
        "claim_id": null,
        "evidence": null,
        "primary": true,
        "role": null,
        "valid_from": null,
        "valid_to": null
      },
      {
        "predicate": "subtype_of",
        "label": "Has subtype",
        "clinical_claim_not_fact": false,
        "family": "navigation",
        "other_entity_id": "cardio:mitral-regurgitation",
        "other_entity_in_atlas": true,
        "claim_id": null,
        "evidence": null,
        "primary": true,
        "role": null,
        "valid_from": null,
        "valid_to": null
      },
      {
        "predicate": "related_to",
        "label": "Related to",
        "clinical_claim_not_fact": false,
        "family": "navigation",
        "other_entity_id": "cardio:rheumatic-heart-disease",
        "other_entity_in_atlas": true,
        "claim_id": null,
        "evidence": null,
        "primary": false,
        "role": null,
        "valid_from": null,
        "valid_to": null
      },
      {
        "predicate": "evaluated_for",
        "label": "Evaluated for this",
        "clinical_claim_not_fact": true,
        "family": "clinical",
        "other_entity_id": "cardio:triclip",
        "other_entity_in_atlas": true,
        "claim_id": "cardio:claim-triluminate-primary",
        "evidence": null,
        "primary": false,
        "role": null,
        "valid_from": null,
        "valid_to": null
      },
      {
        "predicate": "investigates",
        "label": "Investigated in",
        "clinical_claim_not_fact": false,
        "family": "sourced",
        "other_entity_id": "cardio:triluminate",
        "other_entity_in_atlas": true,
        "claim_id": null,
        "evidence": {
          "snapshot_id": "cardio:ctgov-nct03904147-2026-10-14",
          "locator": "protocolSection.conditionsModule.conditions[0]"
        },
        "primary": false,
        "role": null,
        "valid_from": null,
        "valid_to": null
      },
      {
        "predicate": "related_to",
        "label": "Related to",
        "clinical_claim_not_fact": false,
        "family": "navigation",
        "other_entity_id": "cardio:transcatheter-edge-to-edge-repair",
        "other_entity_in_atlas": true,
        "claim_id": null,
        "evidence": null,
        "primary": false,
        "role": null,
        "valid_from": null,
        "valid_to": null
      }
    ]
  },
  "page_path": "conditions/heart-valve-disease/",
  "context_path": "api/v1/context/cardio--heart-valve-disease.md"
}