{
  "release_id": "f6f6f1b6f50379ed",
  "id": "cardio:coronary-artery-disease",
  "owner": "cardio",
  "kind": "condition",
  "slug": "coronary-artery-disease",
  "name": "Coronary artery disease",
  "aliases": [
    "CAD",
    "Coronary heart disease",
    "Ischemic heart disease"
  ],
  "atlases": [
    "cardio"
  ],
  "summary_plain": "Coronary artery disease happens when fatty deposits, called plaque, build up in the arteries that feed the heart muscle and narrow them, so the heart may not get the blood it needs. Many people find out only when chest pain, a heart attack or a cardiac arrest occurs. It is the cause of most heart attacks.",
  "summary_technical": "NHLBI uses the name coronary heart disease and gives coronary artery disease and ischemic heart disease as other names for it. NHLBI reports 371,506 US deaths from it in 2022 and estimates that one in every twenty US adults aged 20 and over has it. MedlinePlus describes it as the leading form of heart disease in the United States. This page is the hub for the atlas records on LDL-lowering medicines, stents and anti-inflammatory treatment.",
  "editorial_state": "draft",
  "last_substantive_edit": "2026-10-14",
  "last_evidence_check": "2026-10-14",
  "next_review_due": null,
  "identifiers": [
    {
      "scheme": "mesh",
      "value": "D003324",
      "normalized_value": "D003324",
      "match": "exact",
      "version": "MeSH linked-data descriptor record fetched on 2026-10-14, lastUpdated 2020-01-16; the record states no yearly MeSH release",
      "label": null,
      "from_source": false
    }
  ],
  "navigation": {
    "cardio": {
      "system": [
        "heart"
      ],
      "condition-area": [
        "coronary-and-vascular-disease"
      ]
    }
  },
  "payload": {
    "recognition": "NHLBI notes that symptoms differ between people and that many learn of the disease only when chest pain, a heart attack or cardiac arrest occurs.",
    "assessment": null,
    "burden_claims": []
  },
  "content_digest": "71e69e880f6f2a551628da324702c9cbd0526544f202d83f3d3ee7cffdbc0e67",
  "review": {
    "content_digest": "71e69e880f6f2a551628da324702c9cbd0526544f202d83f3d3ee7cffdbc0e67",
    "current": [],
    "conflicting": [],
    "stale": [],
    "inactive": []
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  "claims": [
    {
      "release_id": "f6f6f1b6f50379ed",
      "id": "cardio:claim-cad-can-cause-heart-attack",
      "owner": "cardio",
      "subject_entity_id": "cardio:coronary-artery-disease",
      "category": "descriptive",
      "statement": "According to NHLBI, coronary artery disease is behind most heart attacks. MedlinePlus describes a heart attack as blood flow to the heart suddenly becoming blocked.",
      "context": {
        "id": "cardio:ctx-nhlbi-medlineplus-adults-coronary-pages",
        "label": "Adults, general patient-education statements on NHLBI and MedlinePlus pages about coronary disease, heart attack and cholesterol",
        "recipient": "adult",
        "population": "Adults in general. The pages are written for the public and give no study population, age range or risk group for these statements.",
        "care_setting": "General health information for the public; no care setting is stated",
        "geography": "United States (pages of US government agencies; some figures on them are US statistics)",
        "life_stage_note": "Adults. The NHLBI coronary page gives a prevalence for adults aged 20 and older.",
        "life_stage_terms": null,
        "gestational_age_min_days": null,
        "gestational_age_max_days": null,
        "gestational_age_basis": null,
        "postnatal_age_min_days": null,
        "postnatal_age_max_days": null,
        "gestational_age_status": null,
        "postnatal_age_status": null,
        "followup_description": "Not applicable (descriptive statement)",
        "eligibility": {
          "inclusion": [],
          "exclusion": []
        }
      },
      "evidence_stage": "unknown",
      "certainty": "not_assessed",
      "certainty_method": null,
      "limitations": "Patient-education pages from two US government sources. They give no study, no size of risk and no population, and they do not say how often coronary artery disease leads to a heart attack beyond the word most.",
      "editorial_state": "draft",
      "checked_at": "2026-10-14",
      "next_review_due": null,
      "valid_from": null,
      "valid_to": null,
      "citations": [
        {
          "evidence_role": "supports",
          "locator": "Page body, overview",
          "applicability_note": "NHLBI overview of a heart attack, last updated March 24, 2022 according to the page.",
          "snapshot": {
            "id": "cardio:nhlbi-heart-attack-2026-10-14",
            "retrieved_at": "2026-10-14T18:21:38Z",
            "content_hash": "fecca0b485d427773d2af873968735d814e08bc1ca072e0649444dc29cb5818a",
            "source_effective_date": null,
            "public_archive_url": null,
            "source_state": "current"
          },
          "source": {
            "id": "cardio:nhlbi-heart-attack",
            "source_type": "webpage",
            "title": "Heart Attack: What Is a Heart Attack? (NHLBI)",
            "canonical_url": "https://www.nhlbi.nih.gov/health/heart-attack",
            "identifiers": [],
            "publication_date": null,
            "publisher": "National Heart, Lung, and Blood Institute (NIH)",
            "edition": "Page fetched 2026-10-14. The page states it was last updated on March 24, 2022.",
            "reuse_basis": "NHLBI is a US federal agency, but the NIH web policies page returned HTTP 403 to a script on 2026-10-14 (fetched as cg-nih-web-policies.html, sha256 f31e6a4158180b360f81343218dd81bd4338cd6e85ea8de0386fbdc55ce523f7), so the page-level reuse terms were not read and are unverified. Only the hash of the page is kept. Public text is cite_only until the integration owner confirms the terms.",
            "public_text": "cite_only"
          }
        },
        {
          "evidence_role": "context",
          "locator": "Summary, What is a heart attack?: \"It happens when blood flow to the heart suddenly becomes blocked.\"",
          "applicability_note": "MedlinePlus wording for what a heart attack is.",
          "snapshot": {
            "id": "cardio:medlineplus-heartattack-2026-10-14",
            "retrieved_at": "2026-10-14T18:21:44Z",
            "content_hash": "0071942340d0f832dddcbd79cd237b2bae7908a26cc9ff2a3a6b8c7a0107819e",
            "source_effective_date": null,
            "public_archive_url": null,
            "source_state": "current"
          },
          "source": {
            "id": "cardio:medlineplus-heartattack",
            "source_type": "webpage",
            "title": "Heart Attack (MedlinePlus health topic)",
            "canonical_url": "https://medlineplus.gov/heartattack.html",
            "identifiers": [],
            "publication_date": null,
            "publisher": "U.S. National Library of Medicine (MedlinePlus)",
            "edition": "Page fetched 2026-10-14.",
            "reuse_basis": "MedlinePlus states that works produced by the federal government are not copyrighted, and lists the summaries on health topic pages and Genetics pages as public domain (the page titled Linking to and Using Content from MedlinePlus, fetched as cg-medlineplus-usingcontent.html, sha256 31267ce9db016893b80c5665312d92ffc8c34ec86916f84708c353936ba52228). It names the A.D.A.M. encyclopedia, drug monographs and many images as copyrighted; this atlas uses only the page summary text. The raw page is committed at research/snapshots/cg-medlineplus-heartattack.html.",
            "public_text": "quote"
          }
        }
      ],
      "review": {
        "content_digest": "b192a8bd87aee77af2de5b20da551075724319668345dd3730a7a6e4ad9a2189",
        "current": [],
        "conflicting": [],
        "stale": [],
        "inactive": []
      },
      "api_path": "api/v1/claims/cardio--claim-cad-can-cause-heart-attack.json"
    }
  ],
  "decisions": [],
  "milestones": [],
  "relationships": {
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        "family": "clinical",
        "other_entity_id": "cardio:myocardial-infarction",
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        "claim_id": "cardio:claim-cad-can-cause-heart-attack",
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        "other_entity_id": "cardio:lipoprotein-a",
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}