{ "release_id": "2b2017b84496b985", "id": "cardio:bp-lowering-to-target", "owner": "cardio", "kind": "intervention", "slug": "bp-lowering-to-target", "name": "Blood-pressure lowering to a target", "aliases": [], "atlases": [ "cardio" ], "summary_plain": "Using medicines and lifestyle changes to bring blood pressure below a chosen number and keep it there.", "summary_technical": "Generic treat-to-target antihypertensive management. The target belongs to the guideline context or study arm, not to this entity.", "editorial_state": "draft", "last_substantive_edit": "2026-10-09", "last_evidence_check": null, "next_review_due": null, "external_ids": [], "navigation": { "cardio": { "system": [ "blood-vessels" ], "condition-area": [ "hypertension" ] } }, "payload": { "subtype": "medicine", "mechanism": null, "taxonomy_codes": [] }, "content_digest": "d33c9d683bed068fb711c5cecbb97b48466f27aa03f2ed47581a139eda082709", "review": { "content_digest": "d33c9d683bed068fb711c5cecbb97b48466f27aa03f2ed47581a139eda082709", "current": [], "conflicting": [], "stale": [], "inactive": [] }, "claims": [ { "release_id": "2b2017b84496b985", "id": "cardio:claim-esc-2024-on-treatment-target", "owner": "cardio", "subject_entity_id": "cardio:bp-lowering-to-target", "category": "recommendation", "statement": "The European Society of Cardiology's summary of its 2024 guideline gives 120 to 129 mmHg systolic and 70 to 79 mmHg diastolic as the pressure to aim for during treatment in all adults, if the treatment is well tolerated. It says the aim is the same whatever the pressure at which treatment is advised to start. It also says there are a number of important exceptions, and that decisions made for the individual patient always come first.", "context": { "id": "cardio:ctx-esc-2024-adults", "label": "Adults with elevated blood pressure or hypertension (2024 ESC guideline)", "recipient": "adult", "population": "Adults with elevated blood pressure or hypertension. Age limits and pregnancy handling are not stated in the sources read.", "care_setting": "Not stated in the sources read", "geography": "Not stated in the sources read (guideline of the European Society of Cardiology; applicability by country not verified)", "life_stage": "Adult", "gestational_age_min_days": null, "gestational_age_max_days": null, "postnatal_age_min_days": null, "postnatal_age_max_days": null, "gestational_age_status": null, "postnatal_age_status": null, "followup_description": "Not applicable (guideline context)", "eligibility": { "inclusion": [ "Adults with elevated blood pressure or hypertension" ], "exclusion": [] } }, "evidence_stage": "guidance", "certainty": "not_assessed", "certainty_method": null, "limitations": "The source is the ESC's condensed Essential Messages, not the recommendation tables, so the class of recommendation, the level of evidence, the exceptions and the pressure at which to start treatment were not read. This is a claim only and has no recommendation decision. Two later corrections are listed in PubMed, their text was not read, and the Essential Messages was produced before both, so whether the corrections change the target given here is unknown. Any other guideline states its own target. A claim about another guideline is recorded separately and is not reconciled with this one, so this claim does not say which target is right. Pregnancy handling is not stated in the sources read.", "editorial_state": "draft", "checked_at": null, "next_review_due": null, "valid_from": null, "valid_to": null, "citations": [ { "evidence_role": "supports", "locator": "Section 1 Key messages, message 10", "applicability_note": "ESC Essential Messages PDF for the 2024 guideline.", "snapshot": { "id": "cardio:esc-essential-messages-2026-10-11", "retrieved_at": "2026-10-11T19:13:32Z", "content_hash": "1002525ded65298879e25304fbc88d4af91631b7dd4977df3ec2e67f504ffd98", "source_effective_date": null, "public_archive_url": null, "source_state": "corrected" }, "source": { "id": "cardio:esc-2024-hypertension", "source_type": "guideline", "title": "2024 ESC Guidelines for the management of elevated blood pressure and hypertension", "canonical_url": "https://doi.org/10.1093/eurheartj/ehae178", "identifier_namespace": "doi", "identifier_value": "10.1093/eurheartj/ehae178", "publication_date": "2024-08-30", "publisher": "Oxford University Press (OUP)", "edition": "Issued by the European Society of Cardiology and published in European Heart Journal 45(38):3912-4018. The publisher field is the journal publisher as Crossref names it. Publisher summary only. The version of record was not read: doi.org and academic.oup.com returned HTTP 403 (a Cloudflare challenge), PubMed holds no abstract for it, and Europe PMC lists it as subscription required. The facts come from the ESC Essential Messages PDF for this guideline, found through the ESC Essential messages page, and from the ESC guideline page. Two later corrections are listed in PubMed (Eur Heart J 2025 Apr 7;46(14):1300, doi 10.1093/eurheartj/ehaf031, and 2025 Dec 1;46(45):4949, doi 10.1093/eurheartj/ehaf659). Their text was not read, and the Essential Messages was produced before both.", "reuse_basis": "Hashes only and nothing committed. The ESC states that its guidelines are protected by copyright, are for personal and educational use with no commercial use, and that it reserves the right to license use of its guidelines for training generative AI (EU Directive 2019/790, Article 4 section 3). Public text is cite_only (Ben's decision of 2026-10-13 (medical-atlas-core issue 2)): public pages state the ESC's recommendations in the atlas's own words, with a citation and a link, and use no ESC wording.", "public_text": "cite_only" } }, { "evidence_role": "context", "locator": "Back page, corrections notice", "applicability_note": "The ESC says it posts corrections and updates made after publication on its guidelines page.", "snapshot": { "id": "cardio:esc-essential-messages-2026-10-11", "retrieved_at": "2026-10-11T19:13:32Z", "content_hash": "1002525ded65298879e25304fbc88d4af91631b7dd4977df3ec2e67f504ffd98", "source_effective_date": null, "public_archive_url": null, "source_state": "corrected" }, "source": { "id": "cardio:esc-2024-hypertension", "source_type": "guideline", "title": "2024 ESC Guidelines for the management of elevated blood pressure and hypertension", "canonical_url": "https://doi.org/10.1093/eurheartj/ehae178", "identifier_namespace": "doi", "identifier_value": "10.1093/eurheartj/ehae178", "publication_date": "2024-08-30", "publisher": "Oxford University Press (OUP)", "edition": "Issued by the European Society of Cardiology and published in European Heart Journal 45(38):3912-4018. The publisher field is the journal publisher as Crossref names it. Publisher summary only. The version of record was not read: doi.org and academic.oup.com returned HTTP 403 (a Cloudflare challenge), PubMed holds no abstract for it, and Europe PMC lists it as subscription required. The facts come from the ESC Essential Messages PDF for this guideline, found through the ESC Essential messages page, and from the ESC guideline page. Two later corrections are listed in PubMed (Eur Heart J 2025 Apr 7;46(14):1300, doi 10.1093/eurheartj/ehaf031, and 2025 Dec 1;46(45):4949, doi 10.1093/eurheartj/ehaf659). Their text was not read, and the Essential Messages was produced before both.", "reuse_basis": "Hashes only and nothing committed. The ESC states that its guidelines are protected by copyright, are for personal and educational use with no commercial use, and that it reserves the right to license use of its guidelines for training generative AI (EU Directive 2019/790, Article 4 section 3). Public text is cite_only (Ben's decision of 2026-10-13 (medical-atlas-core issue 2)): public pages state the ESC's recommendations in the atlas's own words, with a citation and a link, and use no ESC wording.", "public_text": "cite_only" } }, { "evidence_role": "context", "locator": "CommentsCorrectionsList, two ErratumIn entries", "applicability_note": "Shows that two corrections exist. What they change is unknown.", "snapshot": { "id": "cardio:pubmed-39210715-2026-10-11", "retrieved_at": "2026-10-11T19:12:57Z", "content_hash": "f9afb12c7dd4e0a09ed8cba2fbbc89cf98fe1655ea1bfe1bb04012b061740281", "source_effective_date": null, "public_archive_url": null, "source_state": "corrected" }, "source": { "id": "cardio:esc-2024-hypertension", "source_type": "guideline", "title": "2024 ESC Guidelines for the management of elevated blood pressure and hypertension", "canonical_url": "https://doi.org/10.1093/eurheartj/ehae178", "identifier_namespace": "doi", "identifier_value": "10.1093/eurheartj/ehae178", "publication_date": "2024-08-30", "publisher": "Oxford University Press (OUP)", "edition": "Issued by the European Society of Cardiology and published in European Heart Journal 45(38):3912-4018. The publisher field is the journal publisher as Crossref names it. Publisher summary only. The version of record was not read: doi.org and academic.oup.com returned HTTP 403 (a Cloudflare challenge), PubMed holds no abstract for it, and Europe PMC lists it as subscription required. The facts come from the ESC Essential Messages PDF for this guideline, found through the ESC Essential messages page, and from the ESC guideline page. Two later corrections are listed in PubMed (Eur Heart J 2025 Apr 7;46(14):1300, doi 10.1093/eurheartj/ehaf031, and 2025 Dec 1;46(45):4949, doi 10.1093/eurheartj/ehaf659). Their text was not read, and the Essential Messages was produced before both.", "reuse_basis": "Hashes only and nothing committed. The ESC states that its guidelines are protected by copyright, are for personal and educational use with no commercial use, and that it reserves the right to license use of its guidelines for training generative AI (EU Directive 2019/790, Article 4 section 3). Public text is cite_only (Ben's decision of 2026-10-13 (medical-atlas-core issue 2)): public pages state the ESC's recommendations in the atlas's own words, with a citation and a link, and use no ESC wording.", "public_text": "cite_only" } } ], "review": { "content_digest": "4226cc14f23060adb09ca5ac584cd43837290c7f4b7bedf0119b34ea5ad8170b", "current": [], "conflicting": [], "stale": [], "inactive": [] }, "api_path": "api/v1/claims/cardio--claim-esc-2024-on-treatment-target.json" }, { "release_id": "2b2017b84496b985", "id": "cardio:claim-nice-ng136-target-under-80", "owner": "cardio", "subject_entity_id": "cardio:bp-lowering-to-target", "category": "recommendation", "statement": "NICE guideline NG136 recommends lowering clinic blood pressure below 140/90 mmHg, and keeping it there, for adults with hypertension aged under 80.", "context": { "id": "cardio:ctx-nice-adults-under-80-hypertension", "label": "Adults with hypertension aged under 80 (NICE NG136 recommendation 1.4.20)", "recipient": "adult", "population": "Adults with hypertension aged under 80, with or without type 2 diabetes (NG136 Table 1)", "care_setting": "Not stated on the fetched page", "geography": "Not stated on the fetched page (NICE guidance; jurisdiction not verified)", "life_stage": "Adult under 80", "gestational_age_min_days": null, "gestational_age_max_days": null, "postnatal_age_min_days": null, "postnatal_age_max_days": null, "gestational_age_status": null, "postnatal_age_status": null, "followup_description": "Not applicable (recommendation context)", "eligibility": { "inclusion": [ "Adult with hypertension", "Aged under 80", "With or without type 2 diabetes (NG136 Table 1)" ], "exclusion": [] } }, "evidence_stage": "guidance", "certainty": "not_assessed", "certainty_method": null, "limitations": "NICE's population includes people with type 2 diabetes, whom SPRINT excluded. The fetched page gives no strength label for this imperative wording (a pair of directive verbs, one to lower the pressure and one to keep it there), and NICE's page on recommendation wording explains only the verbs offer and consider. The jurisdiction is not stated on the fetched page. The recommendation carries the tag 2019, amended 2022; the exact amendment date was not recorded. This claim records what NICE recommends. It does not say that NICE assessed or rejected SPRINT's target.", "editorial_state": "draft", "checked_at": null, "next_review_due": null, "valid_from": null, "valid_to": null, "citations": [ { "evidence_role": "supports", "locator": "Recommendation 1.4.20, the sentence on adults aged under 80", "applicability_note": "NICE NG136 as shown on 2026-10-09, last updated 2026-02-26.", "snapshot": { "id": "cardio:nice-ng136-recs-2026-10-09", "retrieved_at": "2026-10-09T15:59:21Z", "content_hash": "68ce72f3487ffa4715f92ddfa8aaf6e093f5aecd3598cd59a0ab58f74ce86f28", "source_effective_date": "2026-02-26", "public_archive_url": null, "source_state": "current" }, "source": { "id": "cardio:nice-ng136", "source_type": "guideline", "title": "Hypertension in adults: diagnosis and management (NICE guideline NG136), Recommendations chapter", "canonical_url": "https://www.nice.org.uk/guidance/ng136/chapter/Recommendations", "identifier_namespace": "nice", "identifier_value": "NG136", "publication_date": "2019-08-28", "publisher": "National Institute for Health and Care Excellence (NICE)", "edition": "The Recommendations chapter as shown on 2026-10-09 and fetched again on 2026-10-11 with identical bytes. The page header gives 26 February 2026 as the last update. This atlas cites six recommendations from it, each with the version tag the page shows: 1.1.3 is tagged [2004]; 1.2.3, 1.2.4 and 1.2.8 are tagged [2019]; 1.4.5 is tagged [2004, amended 2019]; 1.4.20 is tagged [2019, amended 2022]. Which edition of each recommendation these tags point to was not checked.", "reuse_basis": "Public text is cite_only (Ben's decision of 2026-10-13 (medical-atlas-core issue 2)): public pages state the facts in the atlas's own words, with a citation and a link, and use no NICE wording. NICE's terms and conditions (source cardio:nice-terms-and-conditions, fetched 2026-10-11) make NICE content available for reuse in the United Kingdom only. Outside the United Kingdom, apart from private use, study or one's own research, reuse needs NICE's prior written agreement, which may carry a licence and a fee, and use for artificial intelligence needs approval and a licensing arrangement. The terms also say NICE does not write its content as a basis for decisions outside the United Kingdom. The page bytes are not committed.", "public_text": "cite_only" } }, { "evidence_role": "context", "locator": "Recommendation 1.4.20, version tag", "applicability_note": "Dates the wording of this recommendation.", "snapshot": { "id": "cardio:nice-ng136-recs-2026-10-09", "retrieved_at": "2026-10-09T15:59:21Z", "content_hash": "68ce72f3487ffa4715f92ddfa8aaf6e093f5aecd3598cd59a0ab58f74ce86f28", "source_effective_date": "2026-02-26", "public_archive_url": null, "source_state": "current" }, "source": { "id": "cardio:nice-ng136", "source_type": "guideline", "title": "Hypertension in adults: diagnosis and management (NICE guideline NG136), Recommendations chapter", "canonical_url": "https://www.nice.org.uk/guidance/ng136/chapter/Recommendations", "identifier_namespace": "nice", "identifier_value": "NG136", "publication_date": "2019-08-28", "publisher": "National Institute for Health and Care Excellence (NICE)", "edition": "The Recommendations chapter as shown on 2026-10-09 and fetched again on 2026-10-11 with identical bytes. The page header gives 26 February 2026 as the last update. This atlas cites six recommendations from it, each with the version tag the page shows: 1.1.3 is tagged [2004]; 1.2.3, 1.2.4 and 1.2.8 are tagged [2019]; 1.4.5 is tagged [2004, amended 2019]; 1.4.20 is tagged [2019, amended 2022]. Which edition of each recommendation these tags point to was not checked.", "reuse_basis": "Public text is cite_only (Ben's decision of 2026-10-13 (medical-atlas-core issue 2)): public pages state the facts in the atlas's own words, with a citation and a link, and use no NICE wording. NICE's terms and conditions (source cardio:nice-terms-and-conditions, fetched 2026-10-11) make NICE content available for reuse in the United Kingdom only. Outside the United Kingdom, apart from private use, study or one's own research, reuse needs NICE's prior written agreement, which may carry a licence and a fee, and use for artificial intelligence needs approval and a licensing arrangement. The terms also say NICE does not write its content as a basis for decisions outside the United Kingdom. The page bytes are not committed.", "public_text": "cite_only" } }, { "evidence_role": "context", "locator": "Section on recommendation wording, the sentence on the verb offer", "applicability_note": "Explains how NICE uses the verb offer. It does not say what strength imperative verbs such as reduce carry.", "snapshot": { "id": "cardio:nice-making-decisions-2026-10-09", "retrieved_at": "2026-10-09T15:59:49Z", "content_hash": "b7838d1bdb692f2b6dfc71480aa95803d68c64aa0dde406375953c9479aaae7c", "source_effective_date": null, "public_archive_url": null, "source_state": "current" }, "source": { "id": "cardio:nice-making-decisions", "source_type": "webpage", "title": "Making decisions using NICE guidelines", "canonical_url": "https://www.nice.org.uk/about/what-we-do/our-programmes/nice-guidance/nice-guidelines/making-decisions-using-nice-guidelines", "identifier_namespace": null, "identifier_value": null, "publication_date": null, "publisher": "National Institute for Health and Care Excellence (NICE)", "edition": null, "reuse_basis": "Public text is cite_only (Ben's decision of 2026-10-13 (medical-atlas-core issue 2)): public pages state the facts in the atlas's own words, with a citation and a link, and use no NICE wording. NICE's terms and conditions (source cardio:nice-terms-and-conditions, fetched 2026-10-11) make NICE content available for reuse in the United Kingdom only; outside it, apart from private use, study or one's own research, NICE's prior written agreement is needed.", "public_text": "cite_only" } } ], "review": { "content_digest": "912cf87da4178012a890476ad5bbc3f1982c69401353fc967977a8b50d9fe715", "current": [], "conflicting": [], "stale": [], "inactive": [] }, "api_path": "api/v1/claims/cardio--claim-nice-ng136-target-under-80.json" }, { "release_id": "2b2017b84496b985", "id": "cardio:claim-who-2021-r6a", "owner": "cardio", "subject_entity_id": "cardio:bp-lowering-to-target", "category": "recommendation", "statement": "WHO recommends a blood pressure target of below 140/90 mmHg for adults with hypertension who have no comorbidities.", "context": { "id": "cardio:ctx-who-2021-adults-hypertension-no-comorbidities", "label": "Adults with hypertension without comorbidities (WHO 2021 recommendation 6a)", "recipient": "adult", "population": "Adults with hypertension and no comorbidities. The recommendation statement does not define comorbidities. The rationale on the same page (PDF page 28) names them: \"In patients with comorbidity (CAD, DM, CKD) there is consistent benefit with lower targets\", where WHO's list of acronyms gives CAD as coronary artery disease, DM as diabetes mellitus and CKD as chronic kidney disease. WHO says the guideline targets non-pregnant adults.", "care_setting": "Not stated for this recommendation in the source", "geography": "Global WHO guidance; national adoption not recorded", "life_stage": "Adult", "gestational_age_min_days": null, "gestational_age_max_days": null, "postnatal_age_min_days": null, "postnatal_age_max_days": null, "gestational_age_status": null, "postnatal_age_status": null, "followup_description": "Not applicable (recommendation context)", "eligibility": { "inclusion": [ "Adult", "Hypertension", "No comorbidities" ], "exclusion": [ "Pregnant patients: WHO says the recommendations target non-pregnant patients" ] } }, "evidence_stage": "guidance", "certainty": "moderate", "certainty_method": "The certainty is the GRADE level WHO prints in the strength label of this recommendation. It is WHO's assessment of the evidence base, not an assessment by this atlas.", "limitations": "WHO labels this statement \"Strong recommendation, moderate-certainty evidence\". The certainty above is that label. The recommendation statement does not define comorbidities. The rationale on the same page (PDF page 28) names them: \"In patients with comorbidity (CAD, DM, CKD) there is consistent benefit with lower targets\", where WHO's list of acronyms gives CAD as coronary artery disease, DM as diabetes mellitus and CKD as chronic kidney disease. Statements 6b and 6c set a lower systolic target for two other groups. NICE sets its own target in a separate claim. Global WHO guidance written for adults who are not pregnant; national adoption is not recorded. No evidence review behind the recommendation was read by this cluster. The WHO publication page and the PDF disagree on the page count (48 versus 61); this was not resolved.", "editorial_state": "draft", "checked_at": "2026-10-11", "next_review_due": null, "valid_from": null, "valid_to": null, "citations": [ { "evidence_role": "supports", "locator": "PDF page 28, section 3.6, recommendation 6, first statement", "applicability_note": "The target and the population.", "snapshot": { "id": "cardio:who-9789240033986-eng-pdf-2026-10-11", "retrieved_at": "2026-10-11T19:11:40Z", "content_hash": "57f6376d5c9bc4ea6c44873625547c8a5443d5a6ad8c8c422733681563db05fb", "source_effective_date": "2021-08-24", "public_archive_url": null, "source_state": "current" }, "source": { "id": "cardio:who-2021-hypertension-pharmacological", "source_type": "guideline", "title": "Guideline for the pharmacological treatment of hypertension in adults (World Health Organization, 2021)", "canonical_url": "https://www.who.int/publications/i/item/9789240033986", "identifier_namespace": "isbn", "identifier_value": "978-92-4-003398-6", "publication_date": "2021-08-24", "publisher": "World Health Organization", "edition": "Two snapshots of one edition, fetched on 2026-10-11: the WHO publication page, and the English PDF through the IRIS REST bitstream (843539 bytes, 61 pages counted from the file). The publication page states 48 pages. This cluster did not resolve the difference. A separate WHO summary edition exists and was not fetched.", "reuse_basis": "CC BY-NC-SA 3.0 IGO, as the PDF states. Short quotations with attribution only. The non-commercial and share-alike terms need a decision on the atlas public data licence before any reuse beyond short quotation. Neither snapshot is committed.", "public_text": "quote" } }, { "evidence_role": "context", "locator": "PDF page 28, section 3.6, recommendation 6, first statement, strength label", "applicability_note": "The strength label WHO prints under the statement: Strong recommendation, moderate-certainty evidence", "snapshot": { "id": "cardio:who-9789240033986-eng-pdf-2026-10-11", "retrieved_at": "2026-10-11T19:11:40Z", "content_hash": "57f6376d5c9bc4ea6c44873625547c8a5443d5a6ad8c8c422733681563db05fb", "source_effective_date": "2021-08-24", "public_archive_url": null, "source_state": "current" }, "source": { "id": "cardio:who-2021-hypertension-pharmacological", "source_type": "guideline", "title": "Guideline for the pharmacological treatment of hypertension in adults (World Health Organization, 2021)", "canonical_url": "https://www.who.int/publications/i/item/9789240033986", "identifier_namespace": "isbn", "identifier_value": "978-92-4-003398-6", "publication_date": "2021-08-24", "publisher": "World Health Organization", "edition": "Two snapshots of one edition, fetched on 2026-10-11: the WHO publication page, and the English PDF through the IRIS REST bitstream (843539 bytes, 61 pages counted from the file). The publication page states 48 pages. This cluster did not resolve the difference. A separate WHO summary edition exists and was not fetched.", "reuse_basis": "CC BY-NC-SA 3.0 IGO, as the PDF states. Short quotations with attribution only. The non-commercial and share-alike terms need a decision on the atlas public data licence before any reuse beyond short quotation. Neither snapshot is committed.", "public_text": "quote" } }, { "evidence_role": "context", "locator": "PDF page 28, section 3.6, Evidence and rationale, sentence on comorbidity (CAD, DM, CKD)", "applicability_note": "The comorbidities WHO names beside the statement.", "snapshot": { "id": "cardio:who-9789240033986-eng-pdf-2026-10-11", "retrieved_at": "2026-10-11T19:11:40Z", "content_hash": "57f6376d5c9bc4ea6c44873625547c8a5443d5a6ad8c8c422733681563db05fb", "source_effective_date": "2021-08-24", "public_archive_url": null, "source_state": "current" }, "source": { "id": "cardio:who-2021-hypertension-pharmacological", "source_type": "guideline", "title": "Guideline for the pharmacological treatment of hypertension in adults (World Health Organization, 2021)", "canonical_url": "https://www.who.int/publications/i/item/9789240033986", "identifier_namespace": "isbn", "identifier_value": "978-92-4-003398-6", "publication_date": "2021-08-24", "publisher": "World Health Organization", "edition": "Two snapshots of one edition, fetched on 2026-10-11: the WHO publication page, and the English PDF through the IRIS REST bitstream (843539 bytes, 61 pages counted from the file). The publication page states 48 pages. This cluster did not resolve the difference. A separate WHO summary edition exists and was not fetched.", "reuse_basis": "CC BY-NC-SA 3.0 IGO, as the PDF states. Short quotations with attribution only. The non-commercial and share-alike terms need a decision on the atlas public data licence before any reuse beyond short quotation. Neither snapshot is committed.", "public_text": "quote" } }, { "evidence_role": "context", "locator": "PDF page 9, Executive summary, paragraph 2, sentence 2", "applicability_note": "WHO scope: adult, non-pregnant patients appropriately diagnosed with hypertension and counselled about lifestyle.", "snapshot": { "id": "cardio:who-9789240033986-eng-pdf-2026-10-11", "retrieved_at": "2026-10-11T19:11:40Z", "content_hash": "57f6376d5c9bc4ea6c44873625547c8a5443d5a6ad8c8c422733681563db05fb", "source_effective_date": "2021-08-24", "public_archive_url": null, "source_state": "current" }, "source": { "id": "cardio:who-2021-hypertension-pharmacological", "source_type": "guideline", "title": "Guideline for the pharmacological treatment of hypertension in adults (World Health Organization, 2021)", "canonical_url": "https://www.who.int/publications/i/item/9789240033986", "identifier_namespace": "isbn", "identifier_value": "978-92-4-003398-6", "publication_date": "2021-08-24", "publisher": "World Health Organization", "edition": "Two snapshots of one edition, fetched on 2026-10-11: the WHO publication page, and the English PDF through the IRIS REST bitstream (843539 bytes, 61 pages counted from the file). The publication page states 48 pages. This cluster did not resolve the difference. A separate WHO summary edition exists and was not fetched.", "reuse_basis": "CC BY-NC-SA 3.0 IGO, as the PDF states. Short quotations with attribution only. The non-commercial and share-alike terms need a decision on the atlas public data licence before any reuse beyond short quotation. 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Neither snapshot is committed.", "public_text": "quote" } } ], "review": { "content_digest": "c12b000d60a7e45eb369988c9b6a3f140c32d3ebde19795cdf62b5d97fe04904", "current": [], "conflicting": [], "stale": [], "inactive": [] }, "api_path": "api/v1/claims/cardio--claim-who-2021-r6c.json" } ], "decisions": [ { "type": "recommendation", "id": "cardio:rec-nice-ng136-1-4-20", "direction": "for", "intervention_id": "cardio:bp-lowering-to-target", "context_id": "cardio:ctx-nice-adults-under-80-hypertension", "guideline_snapshot_id": "cardio:nice-ng136-recs-2026-10-09", "issuer_id": "cardio:nice", "jurisdiction": "Not stated on the fetched page", "strength_label": "Not labeled on the fetched page. The recommendation uses imperative wording (directive verbs to lower the pressure and to keep it there).", "strength_system": "NICE wording convention. 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